Clinical and Technical Working Groups

The Danish National Genome Centre (DNGC) has set up working groups that have advisory functions with reference to DNGC and which work to support the further development of personalised medicine with a particular focus on the use of whole genome sequencing in healthcare and research.

 

Clinical Working Groups 

For each patient group/disease area approved for inclusion in the national infrastructure for whole genome sequencing, a national specialist network is established. The national specialist networks are to provide healthcare expertise and advice on the respective patient group to the National Genome Center (DNGC) for the purpose of national implementation of whole genome sequencing.

The purpose of the national specialist networks is primarily to contribute to achieving the clinical potential for patient access to whole genome sequencing within the specific disease area, within the frameworks established during the decision-making process regarding inclusion. This includes ensuring that patients across the country have equal access to whole genome sequencing through coordinated and uniform implementation and clinical use.

Additionally, the national specialist networks are to advise on the follow-up regarding the clinical effectiveness of the intervention.

 

The Specialist Network has the following overall tasks

  1. Clinical delimitation of the patient group with suggestions for clinical application and number of whole genome sequencing (WGS)
  2. Mapping of the current national set-up for assessment and treatment of the patient group
  3. Follow-up on the implementation of whole genome sequencing for the patient group – assessment of clinical effectiveness

Clinical working groups and specialist networks for selected patient groups

Working Group

The Working Group for Clinical use of Whole Genome Sequencing has been established by the Danish National Genome Center in collaboration with the regions and the Organization of Danish Medical Societies (LVS) to ensure a coordinated effort for the development of whole genome sequencing for clinical use in the healthcare system. The working group for clinical use of whole genome sequencing advises the Steering Group on the selection of patient groups to be offered whole genome sequencing via the Danish National Genome Center.

Mandate and Members (In Danish)

National Specialist Networks 

The National Specialist Network for Rare Diseases has been established by the Danish National Genome Center in collaboration with the regions, the Organization of Danish Medical Societies (LVS) and the Danish Society of Clinical Academics (DSKA).

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on endocrinological patients (e.g. patients with diabetes, goitre and metabolic diseases, osteoporosis, etc.) for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on hereditary haematological disease, incl. children and young people with unresolved cytopenia (patients with blood diseases, e.g. leukaemia) for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on children and young people with cancer (up to 18 years) and hereditary cancer to the Danish National Genome Center for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Cancer in Adults (18-30 Years) and Hereditary Cancer in Adults for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Primary Immune Deficiency Diseases for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Hereditary Heart Diseases for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Haematological Cancer for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Psychiatry Children and Young People under 18 Years of Age for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Kidney Faillure for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Fetal Medicine for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Neurogenetic Patients for use in the national introduction of whole genome sequencing.

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Hereditary cholestatic and fibrotic liver diseases for use in the national implementation of whole genome sequencing.

 Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Audio genetics for use in the national implementation of whole genome sequencing

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Ophthalmology for use in the national implementation of whole genome sequencing

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Rare diseases in children and adults for use in the national implementation of whole genome sequencing

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Severe hereditary skin diseases for use in the national implementation of whole genome sequencing

Mandate and Members (In Danish)

The National Specialist Network must provide health professional advice on Advanced and incurable cancer for use in the national implementation of whole genome sequencing.

Mandate and Members (In Danish)

Technical Working Groups

Mandate and Members (In Danish)

Mandate and Members (In Danish)